Products 143816-42-6
CAS 143816-42-6 appears in our catalog under these names: Quininib, Quininib, 98.1%. Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 500ug, 10mg, 500μg, 500 μg.
Quininib is a styrylquinoline that is trans-2-styrylquinoline in which the the phenyl group has been substituted at position 2 by a hydroxy group. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1. The major species at pH 7.3. It has a role as an angiogenesis inhibitor. It is a styrylquinoline and a member of phenols. It is functionally related to a trans-2-styrylquinoline. It is a conjugate base of a quininib(1+).
Source: ChEBI
| Molecular formula | C17H13NO |
|---|---|
| Molecular weight | 247.29 g/mol |
| IUPAC name | 2-[(E)-2-quinolin-2-ylethenyl]phenol |
| InChIKey | NXNDEWNGCMCWMA-ZRDIBKRKSA-N |
| SMILES | C1=CC=C2C(=C1)C=CC(=N2)/C=C/C3=CC=CC=C3O |
Computed by PubChem (NCBI)
Synonyms:
Quininib, (E)-2-(2-(quinolin-2-yl)vinyl)phenol, 2-[(E)-2-(quinolin-2-yl)vinyl]phenol, 2-[(E)-2-quinolin-2-ylethenyl]phenol, (6E)-6-[(2E)-2-(1H-quinolin-2-ylidene)ethylidene]cyclohexa-2,4-dien-1-one, 2-[(E)-2-(quinolin-2-yl)ethenyl]phenol, 2-[(1E)-2-(quinolin-2-yl)ethenyl]phenol, Cambridge id 5719593, orb1699569, Quininib, >=98% (HPLC)