Products 147127-20-6
CAS 147127-20-6 appears in our catalog under these names: Tenofovir, Tenofovir (1.0 mg/mL in Water), Tenofovir, >95% (HPLC), Tenofovir/ 99.92% (existing batch purity), Tenofovir - Bio-X â„¢. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 5x1ml, 100mg, 10mg, 5mg, 25mg, 50mg, 500mg.
Tenofovir (anhydrous) is a member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. It has a role as an antiviral drug, a drug metabolite and a HIV-1 reverse transcriptase inhibitor. It is a member of phosphonic acids and a nucleoside analogue. It is a conjugate acid of a tenofovir(1-).
Source: ChEBI
| Molecular formula | C9H14N5O4P |
|---|---|
| Molecular weight | 287.21 g/mol |
| IUPAC name | [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid |
| InChIKey | SGOIRFVFHAKUTI-ZCFIWIBFSA-N |
| SMILES | C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O |
Computed by PubChem (NCBI)
Synonyms:
Tenofovir, (R)-9-(2-Phosphonomethoxypropyl)adenine, (R)-PMPA, tenofovir (anhydrous), Tenofovir anhydrous, anhydrous tenofovir, tenofovir (anh.), ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid, [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid, (R)-9-(Phosphonomethoxypropyl)adenine