Products 155229-76-8

CAS 155229-76-8 appears in our catalog under these names: (-)-3S,5R-Fluvastatin sodium salt, 95%, (3S,5R,E)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid, 98%, 98%. Offered by: Combi-blocks, Chemat. Available pack sizes: 1g, 250mg, 5mg, 10mg, 25mg, 50mg.

Structural formula: {0} (CAS {1})

Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. An HMG-CoA reductase inhibitor, it is used (often as the corresponding sodium salt) to reduce triglycerides and LDL-cholesterol, and increase HDL-chloesterol, in the treatment of hyperlipidaemia. It has a role as an anticholesteremic drug and an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor. It is a racemate and a statin (synthetic). It contains a (3R,5S)-fluvastatin and a (3S,5R)-fluvastatin.

Source: ChEBI

Identity
Molecular formulaC24H26FNO4
Molecular weight411.5 g/mol
IUPAC name(E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
InChIKeyFJLGEFLZQAZZCD-JUFISIKESA-N
SMILESCC(C)N1C2=CC=CC=C2C(=C1/C=C/[C@@H](C[C@@H](CC(=O)O)O)O)C3=CC=C(C=C3)F

Computed by PubChem (NCBI)