CAS 1611493-60-7 appears in our catalog under these names: Bictegravir, Bictegravir (100 mg/mL in DMSO), Bictegravir, >95% (HPLC), Bictegravir/ 99.98% (existing batch purity), Bictegravir (GS–9883). Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 1x1ml, 10mg, 1mg, 5mg, 25mg, 50mg, 100mg.
Bictegravir is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid with the amino group of 2,4,6-trifluorobenzylamine. It is a second-generation integrase strand transfer inhibitor (INSTI) and used (as its sodium salt) for the treatment of HIV-1. It has a role as a HIV-1 integrase inhibitor. It is a secondary carboxamide, a monocarboxylic acid amide, an organic heterotetracyclic compound and a trifluorobenzene. It is a conjugate acid of a bictegravir(1-).
Source: ChEBI
| Molecular formula | C21H18F3N3O5 |
|---|---|
| Molecular weight | 449.4 g/mol |
| IUPAC name | (1S,11R,13R)-5-hydroxy-3,6-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-12-oxa-2,9-diazatetracyclo[11.2.1.02,11.04,9]hexadeca-4,7-diene-7-carboxamide |
| InChIKey | SOLUWJRYJLAZCX-LYOVBCGYSA-N |
| SMILES | C1C[C@@H]2C[C@H]1N3[C@H](O2)CN4C=C(C(=O)C(=C4C3=O)O)C(=O)NCC5=C(C=C(C=C5F)F)F |
Computed by PubChem (NCBI)