Products 166977-43-1
CAS 166977-43-1 appears in our catalog under these names: BMS 453, BMS 453, BMS453/ 99.78% (existing batch purity), BMS453 99%, BMS 453, 99%, 99%. Offered by: GLPBio, TRC, TargetMol, Biosynth, Ambeed. Available pack sizes: 1mg, 500mg, 5mg, 10mg, 25mg, 50mg, 100mg, 50 mg.
BMS-453 is a member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. It has a role as a teratogenic agent, a retinoic acid receptor alpha antagonist, a retinoic acid receptor beta agonist and a retinoic acid receptor gamma antagonist. It is a member of benzoic acids, a stilbenoid and a member of dihydronaphthalenes.
Source: ChEBI
| Molecular formula | C27H24O2 |
|---|---|
| Molecular weight | 380.5 g/mol |
| IUPAC name | 4-[(E)-2-(5,5-dimethyl-8-phenyl-6H-naphthalen-2-yl)ethenyl]benzoic acid |
| InChIKey | VUODRPPTYLBGFM-CMDGGOBGSA-N |
| SMILES | CC1(CC=C(C2=C1C=CC(=C2)/C=C/C3=CC=C(C=C3)C(=O)O)C4=CC=CC=C4)C |
Computed by PubChem (NCBI)
Synonyms:
(E)-4-(2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl)benzoic acid, 4-[(E)-2-(5,5-dimethyl-8-phenyl-6H-naphthalen-2-yl)ethenyl]benzoic Acid, E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid, (E)-4-(2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl)benzoicacid, (E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid, orb1704988, 4-[(E)-2-(5,5-dimethyl-8-phenyl-6H-naphthalen-2-yl)vinyl]benzoic acid, 4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid