Products 180084-26-8
CAS 180084-26-8 appears in our catalog under these names: SB-224289 hydrochloride/ 97.82% (existing batch purity), SB 224289 hydrochloride, SB-224289 Hyrochloride, SB-224289 HCl 98%, (2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydro-2H,5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)methanone hydrochloride, 98%, 98%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 5mg, 10mg, 100mg, 25mg, 10mM (in 1ml dmso), 50mg, 250mg, 10 mg.
SB 224289 hydrochloride is a hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo. It has a role as a serotonergic antagonist and a prodrug. It contains a SB 224289(1+).
Source: ChEBI
| Molecular formula | C32H33ClN4O3 |
|---|---|
| Molecular weight | 557.1 g/mol |
| IUPAC name | [4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1'-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4'-piperidine]-5-yl)methanone;hydrochloride |
| InChIKey | GKGKBZYMDILCOF-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)N4CCC5=CC6=C(C=C54)C7(CCN(CC7)C)CO6.Cl |
Computed by PubChem (NCBI)