Products 180916-16-9

CAS 180916-16-9 appears in our catalog under these names: Lasofoxifene, Lasofoxifene, >95% (HPLC), (5R,6S)-6-Phenyl-5-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,6,7,8-tetrahydronaphthalen-2-ol, 99.60% ,, 99.60% ,, Lasofoxifene (Standard), Lasofoxifene, 99.27%. Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Chemat. Available pack sizes: on request, 25mg, 5mg, 10mg, 50mg, 1mg, Get quote, 10 mg.

Lasofoxifene
Chemat Brand, GLPBio, TargetMol
  • size: on request, 10mg, 25mg, 50mg
  • Variants: 8
from 681.29
View product
Lasofoxifene, >95% (HPLC)
TRC
  • size: 25mg, 5mg
  • Variants: 2
View product
(5R,6S)-6-Phenyl-5-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,6,7,8-tetrahydronaphthalen-2-ol, 99.60% ,, 99.60% ,
Chemat
  • size: 5mg, 25mg, 1mg
  • Variants: 3
from 256.40
View product
Lasofoxifene (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
View product
Lasofoxifene, 99.27%
MedChemExpress
  • size: 10 mg, 25 mg, 50 mg, 5 mg
  • Variants: 4
from 435.79
View product
Lasofoxifene-d4
Chemat Brand
  • size: on request
  • Variants: 1
View product
Structural formula: {0} (CAS {1})

Lasofoxifene is a member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women. It has a role as an antineoplastic agent, a bone density conservation agent, an estrogen receptor antagonist, an estrogen receptor agonist and a cardioprotective agent. It is a member of naphthols, an aromatic ether, a member of tetralins and a N-alkylpyrrolidine.

Source: ChEBI

Identity
Molecular formulaC28H31NO2
Molecular weight413.5 g/mol
IUPAC name(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
InChIKeyGXESHMAMLJKROZ-IAPPQJPRSA-N
SMILESC1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: Lasofoxifene, Oporia, lasofoxifeno, lasofoxifenum, rac-Lasofoxifene, Lasofoxifene [INN], Lasofoxifene [INN:BAN], LASOFOXIFENE [MI], LASOFOXIFENE [MART.], LASOFOXIFENE [WHO-DD]
Related forms of this compound
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2
(5R,6S)-6-phenyl-5-[4-(1,1,2,2-tetradeuterio-2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2