Products 180915-78-0

CAS 180915-78-0 is the registry number for rac-Lasofoxifene. Offered by: TRC. Available pack sizes: 10mg, 1mg, 5mg.

rac-Lasofoxifene
TRC
  • size: 10mg, 1mg, 5mg
  • Variants: 3
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Structural formula: {0} (CAS {1})

Lasofoxifene is a member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women. It has a role as an antineoplastic agent, a bone density conservation agent, an estrogen receptor antagonist, an estrogen receptor agonist and a cardioprotective agent. It is a member of naphthols, an aromatic ether, a member of tetralins and a N-alkylpyrrolidine.

Source: ChEBI

Identity
Molecular formulaC28H31NO2
Molecular weight413.5 g/mol
IUPAC name(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
InChIKeyGXESHMAMLJKROZ-IAPPQJPRSA-N
SMILESC1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: Lasofoxifene, Oporia, lasofoxifeno, lasofoxifenum, rac-Lasofoxifene, Lasofoxifene [INN], Lasofoxifene [INN:BAN], LASOFOXIFENE [MI], LASOFOXIFENE [MART.], LASOFOXIFENE [WHO-DD]
Related forms of this compound
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2
(5R,6S)-6-phenyl-5-[4-(1,1,2,2-tetradeuterio-2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2