Products 191102-79-1

CAS 191102-79-1 appears in our catalog under these names: GGTI 2133, GGTI-2133, GGTI-2133/ 99.8% (existing batch purity), GGTI-2133, 98.50%. Offered by: GLPBio, TRC, TargetMol, Chemat, MedChemExpress. Available pack sizes: 1mg, 100mg, 5mg, 10mg, 25mg, 50mg, 500μg, 100 mg.

GGTI 2133
GLPBio
  • size: 1mg, 500μg
  • Variants: 2
from 962.12
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GGTI-2133
TRC, Chemat
  • size: 100mg, 1mg, 5mg, 10mg
  • Variants: 6
from 1763.60
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GGTI-2133/ 99.8% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 1754.02
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GGTI-2133, 98.50%
MedChemExpress
  • size: 100 mg, 10 mg, 10mM/1mL, 50 mg
  • Variants: 7
from 1559.64
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Structural formula: {0} (CAS {1})

GGTI-2133 free base is an N-acyl-L-amino acid obtained by condensation of the carboxy group of 4-{[(imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoic acid with the amino group of L-leucine. An inhibitor of geranylgeranyltransferase type I. It has a role as an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor. It is a N-acyl-L-amino acid, a member of benzamides, a member of imidazoles, a L-leucine derivative, a member of naphthalenes, a substituted aniline, a secondary amino compound and a biaryl. It is a conjugate base of a GGTI-2133 free base(1+).

Source: ChEBI

Identity
Molecular formulaC27H28N4O3
Molecular weight456.5 g/mol
IUPAC name(2S)-2-[[4-(1H-imidazol-5-ylmethylamino)-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoic acid
InChIKeyODTFPKNIFYMEHP-VWLOTQADSA-N
SMILESCC(C)C[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NCC2=CN=CN2)C3=CC=CC4=CC=CC=C43

Computed by PubChem (NCBI)

Synonyms: orb1703426, ODTFPKNIFYMEHP-VWLOTQADSA-N, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-L-leucine, (4-(((1H-Imidazol-4-yl)methyl)amino)-2-(naphthalen-1-yl)benzoyl)-L-leucine, N-[4-{[(1H-imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoyl]-L-leucine