CAS 2192215-81-7 appears in our catalog under these names: Ritlecitinib tosylate, Ritlecitinib tosylate, Ritlecitinib (tosylate), 99.77%, Ritlecitinib (tosylate) (Standard), 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one 4-methylbenzenesulfonate, 99%. Offered by: TargetMol, GLPBio, MedChemExpress, BLDpharm, Chemat. Available pack sizes: 25mg, 50mg, 100mg, 10mg, 5mg, 10mM/1mL, 50 mg, 100 mg.
Ritlecitinib tosylate is an organosulfonate salt obtained by combining equimolar amounts of ritlecitinib and 4-toluenesulfonic acid. It is a kinase inhibitor, developed by Pfizer for the treatment of severe alopecia areata in adults and adolescents 12 years and older. It has a role as an anti-inflammatory drug, an immunosuppressive agent, an antirheumatic drug, a dermatologic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It contains a ritlecitinib(1+).
Source: ChEBI
| Molecular formula | C22H27N5O4S |
|---|---|
| Molecular weight | 457.5 g/mol |
| IUPAC name | 4-methylbenzenesulfonic acid;1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one |
| InChIKey | YOZLVAFWYLSRRN-VZXYPILPSA-N |
| SMILES | C[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3.CC1=CC=C(C=C1)S(=O)(=O)O |
Computed by PubChem (NCBI)