Products 219766-25-3
CAS 219766-25-3 appears in our catalog under these names: ANA 12, 25 mg, ANA 12, ANA 12, 50 mg, ANA-12, ANA-12/ 99.87% (existing batch purity). Offered by: Roth, GLPBio, TRC, TargetMol, Biosynth. Available pack sizes: 25mg, 50mg, 500mg, 1mg, 2mg, 5mg, 10mg, 100mg.
ANA-12 is a secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of alpha-amino--caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B). It has a role as an antidepressant, an anxiolytic drug and a tropomyosin-related kinase B receptor antagonist. It is a secondary carboxamide, a member of caprolactams and a member of 1-benzothiophenes. It is functionally related to a 2-aminohexano-6-lactam and an anthranilic acid.
Source: ChEBI
| Molecular formula | C22H21N3O3S |
|---|---|
| Molecular weight | 407.5 g/mol |
| IUPAC name | N-[2-[(2-oxoazepan-3-yl)carbamoyl]phenyl]-1-benzothiophene-2-carboxamide |
| InChIKey | TUSCYCAIGRVBMD-UHFFFAOYSA-N |
| SMILES | C1CCNC(=O)C(C1)NC(=O)C2=CC=CC=C2NC(=O)C3=CC4=CC=CC=C4S3 |
Computed by PubChem (NCBI)
Synonyms:
N-(2-((2-oxoazepan-3-yl)carbamoyl)phenyl)benzo[b]thiophene-2-carboxamide, N-[2-[(2-oxoazepan-3-yl)carbamoyl]phenyl]-1-benzothiophene-2-carboxamide, N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide, Maybridge1_001394, Oprea1_341312, orb1223183, orb1305599, s7745, N-{2-[(2-oxo-3-azepanyl)carbamoyl]phenyl}-1-benzothiophene-2-carb Oxamide, N-(2-(2-oxoazepan-3-ylcarbamoyl)phenyl)benzo[b]thiophene-2-carboxamide