Products 2654011-51-3
CAS 2654011-51-3 appears in our catalog under these names: HbF inducer 2, 99.38%, 3-(5-(((R)-1-ethylpiperidin-2-yl)methoxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 97%, 97%, HbF inducer 2, 98%. Offered by: MedChemExpress, Chemat, Ambeed. Available pack sizes: 50 mg, 10mM/1mL, 10 mg, 5 mg, 100 mg, 25 mg, 100mg, 250mg.
DWIZ-2 is a member of the class of isoindoles that is 2,3-dihydro-1H-isoindol-1-one substituted by 2,6-dioxopiperidin-3-yl and [(2R)-1-ethylpiperidin-2-yl]methoxy groups at positions 2 and 5, respectively. It is a molecular glue degrader of the WIZ transcription factor that induces fetal hemoglobin in eythroblasts, and a potential therapeutic agent for the treatment of Sickle cell disease. It is a member of isoindoles, a member of piperidines, an aromatic ether, a member of piperidones and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C21H27N3O4 |
|---|---|
| Molecular weight | 385.5 g/mol |
| IUPAC name | 3-[6-[[(2R)-1-ethylpiperidin-2-yl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione |
| InChIKey | DHFJHVJOMHNTSK-NNJIEVJOSA-N |
| SMILES | CCN1CCCC[C@@H]1COC2=CC3=C(C=C2)C(=O)N(C3)C4CCC(=O)NC4=O |
Computed by PubChem (NCBI)