Products 338992-00-0

CAS 338992-00-0 is the registry number for Vandetanib Fumarate. Offered by: TargetMol. Available pack sizes: 25mg, 50mg, 100mg.

Vandetanib Fumarate
TargetMol
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 10732.68
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Structural formula: {0} (CAS {1})

Vandetanib is a quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a member of piperidines, a secondary amine, an aromatic ether, an organobromine compound, an organofluorine compound and a member of quinazolines.

Source: ChEBI

Identity
Molecular formulaC22H24BrFN4O2
Molecular weight475.4 g/mol
IUPAC nameN-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
InChIKeyUHTHHESEBZOYNR-UHFFFAOYSA-N
SMILESCN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

Computed by PubChem (NCBI)

Synonyms: Vandetanib, Zactima, Caprelsa, vandetanibum, vandetanib (zd6474), C22H24BrFN4O2, Vandetanib [INN], 2ivu, Vandetanib [USAN:INN:BAN:JAN], Caprelsa (TN)
Related forms of this compound
N-(4-bromo-2-fluorophenyl)-6-(trideuteriomethoxy)-7-[[1-(trideuteriomethyl)piperidin-4-yl]methoxy]quinazolin-4-amine C22H24BrFN4O2
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine C22H24BrFN4O2