Products 443913-73-3

CAS 443913-73-3 appears in our catalog under these names: Vandetanib, Vandetanib, >95% (HPLC), Vandetanib (ZD6474), Vandetanib - Bio-X â„¢, Vandetanib, >98.0%(HPLC)(T). Offered by: Chemat Brand, TRC, GLPBio, Biosynth, TCI. Available pack sizes: on request, 100mg, 10mg, 5mg, 25mg, 10mM (in 1ml dmso), 0,5g, 0,25g.

Vandetanib
Chemat Brand, Biosynth, Thermo Scientific (Acros)
  • size: on request, 0,5g, 0,25g, 1g
  • Variants: 9
from 350.12
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Vandetanib, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 5mg
  • Variants: 3
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Vandetanib (ZD6474)
GLPBio
  • size: 100mg, 25mg, 10mM (in 1ml dmso)
  • Variants: 3
from 667.25
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Vandetanib - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Vandetanib, >98.0%(HPLC)(T)
TCI
  • size: 200mg, 1g
  • Variants: 2
from 542.72
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Vandetanib, 98.00%
Chemat
  • size: 100mg, 25mg
  • Variants: 2
from 519.40
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4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline, 98%, 98%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 4
from 88.40
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Vandetanib, min. 95 %, BioScience Grade, 10 mg
Roth
  • size: 10mg
  • Variants: 1
from 514.44
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Vandetanib, 250 mg
Roth
  • size: 250mg
  • Variants: 1
from 825.94
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Vandetanib, 500 mg
Roth
  • size: 500mg
  • Variants: 1
from 1297.90
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Vandetanib, 1 g
Roth
  • size: 1g
  • Variants: 1
from 2005.84
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Vandetanib, 2 g
Roth
  • size: 2g
  • Variants: 1
from 3204.61
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Vandetanib, 99.95%
MedChemExpress
  • size: 25 mg, 50 mg, 10 mg, 100 mg
  • Variants: 7
from 287.18
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Vandetanib (Standard)
MedChemExpress
  • size: 100 mg, 50 mg, 25 mg, 5 mg
  • Variants: 5
from 561.18
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Vandetanib, 99%(HPLC),RG
Fluorochem
  • size: 1g, 5g
  • Variants: 2
from 299.91
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Structural formula: {0} (CAS {1})

Vandetanib is a quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a member of piperidines, a secondary amine, an aromatic ether, an organobromine compound, an organofluorine compound and a member of quinazolines.

Source: ChEBI

Identity
Molecular formulaC22H24BrFN4O2
Molecular weight475.4 g/mol
IUPAC nameN-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
InChIKeyUHTHHESEBZOYNR-UHFFFAOYSA-N
SMILESCN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

Computed by PubChem (NCBI)

Synonyms: Vandetanib, Zactima, Caprelsa, vandetanibum, vandetanib (zd6474), C22H24BrFN4O2, Vandetanib [INN], 2ivu, Vandetanib [USAN:INN:BAN:JAN], Caprelsa (TN)
Related forms of this compound
N-(4-bromo-2-fluorophenyl)-6-(trideuteriomethoxy)-7-[[1-(trideuteriomethyl)piperidin-4-yl]methoxy]quinazolin-4-amine C22H24BrFN4O2
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine C22H24BrFN4O2