Products 361442-04-8

CAS 361442-04-8 appears in our catalog under these names: Saxagliptin, Saxagliptin, 98%, Saxagliptin, >95% (HPLC), Saxagliptin/ 99.95% (existing batch purity), Saxagliptin 98% (HPLC). Offered by: Chemat Brand, AmBeed, Mikromol, TRC, GLPBio. Available pack sizes: on request, 5g, 100mg, 10mg, 1mg, 25mg, 5mg, 10mM (in 1ml dmso).

Saxagliptin is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. It is a nitrile, a tertiary alcohol, a monocarboxylic acid amide, an azabicycloalkane and a member of adamantanes.

Source: ChEBI

Identity
Molecular formulaC18H25N3O2
Molecular weight315.4 g/mol
IUPAC name(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
InChIKeyQGJUIPDUBHWZPV-SGTAVMJGSA-N
SMILESC1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N

Computed by PubChem (NCBI)