CAS 58-14-0 appears in our catalog under these names: Pyrimethamine (Daraprim), Pyrimethamine, Pyrimethamine, >95% (HPLC), Pyrimethamine/ 99.74% (existing batch purity), Pyrimethamine, >98.0%(HPLC)(T). Offered by: Chemat Brand, Mikromol, LoGiCal, Dr. Ehrenstorfer, TRC. Available pack sizes: on request, 250mg, 10mg, 100mg, 50mg, 200mg, 10mM (in 1ml dmso), 25g.
Pyrimethamine is an aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis. It has a role as an antiprotozoal drug, an antimalarial and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is an aminopyrimidine and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C12H13ClN4 |
|---|---|
| Molecular weight | 248.71 g/mol |
| IUPAC name | 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |
| InChIKey | WKSAUQYGYAYLPV-UHFFFAOYSA-N |
| SMILES | CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl |
Computed by PubChem (NCBI)