Products 5812-07-7
CAS 5812-07-7 appears in our catalog under these names: SU 4312, NSC 86429, SU4312, 99.74%, SU4312, 98%, 3-(4-(Dimethylamino)benzylidene)indolin-2-one, 98%. Offered by: GLPBio, MedChemExpress, Ambeed, BLDpharm, Sigma-Aldrich. Available pack sizes: 10mg, 100mg, 5mg, 50mg, 5 mg, 10 mg, 50 mg, 25 mg.
SU4312 is a member of the class of oxindoles that is 3-methyleneoxindole in which one of the hydrogens of the methylene group has been replaced by a p-(dimethylamino)phenyl group. SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor. It also inhibits the neuronal nitric oxide synthase (NOS) and exhibits neuroprotection against NO-mediated neurotoxicity. It has a role as a geroprotector, an antineoplastic agent, an angiogenesis inhibitor, a neuroprotective agent and a vascular endothelial growth factor receptor antagonist. It is a member of oxindoles, a substituted aniline and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C17H16N2O |
|---|---|
| Molecular weight | 264.32 g/mol |
| IUPAC name | 3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one |
| InChIKey | UAKWLVYMKBWHMX-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O |
Computed by PubChem (NCBI)
Synonyms:
3-(4-dimethylamino-benzylidenyl)-2-indolinone, 3-(4-Dimethylaminobenzylidenyl)-2-indolinone, DMBI, indolinone, 3-(4-(Dimethylamino)benzylidene)-1,3-dihydro-2H-indol-2-one, 3-[4-(dimethylamino)benzylidene]-1,3-dihydro-2H-indol-2-one, 3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one, dmbi, 3-[4-(dimethylamino)benzylidene]indolin-2-one, 3-(4-(dimethylamino)benzylidene)indolin-2-one, KBioGR_000338