Products 656247-17-5
CAS 656247-17-5 appears in our catalog under these names: Nintedanib (BIBF 1120), Nintedanib (Intedanib), Intedanib, >95% (HPLC), Nintedanib, Nintedanib/ 99.85% (existing batch purity). Offered by: GLPBio, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 5mg, on request, 100mg, 10mg, 50mg, 200mg, 1g, 10mM (in 1ml dmso).
Nintedanib is a member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antifibrotic agent, an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis inhibitor, a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist. It is a methyl ester, an aromatic amine, a member of oxindoles, a N-alkylpiperazine, an enamine, an aromatic ester and an aromatic amide. It is a conjugate base of a nintedanib(1+).
Source: ChEBI
| Molecular formula | C31H33N5O4 |
|---|---|
| Molecular weight | 539.6 g/mol |
| IUPAC name | methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate |
| InChIKey | CPMDPSXJELVGJG-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O |
Computed by PubChem (NCBI)