Products 66934-18-7
CAS 66934-18-7 appears in our catalog under these names: (S)-2-(2-(4-Fluorophenyl)benzo[d]oxazol-5-yl)propanoic acid, 95%, Flunoxaprofen. Offered by: Chemat Brand, MedChemExpress. Available pack sizes: on request, Get quote.
Flunoxaprofen is a monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects. It has a role as a non-steroidal anti-inflammatory drug, an antirheumatic drug, a hepatotoxic agent and a protein kinase C agonist. It is a monocarboxylic acid, an organofluorine compound and a member of 1,3-benzoxazoles. It is functionally related to a propionic acid.
Source: ChEBI
| Molecular formula | C16H12FNO3 |
|---|---|
| Molecular weight | 285.27 g/mol |
| IUPAC name | (2S)-2-[2-(4-fluorophenyl)-1,3-benzoxazol-5-yl]propanoic acid |
| InChIKey | ARPYQKTVRGFPIS-VIFPVBQESA-N |
| SMILES | C[C@@H](C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)F)C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
Flunoxaprofen, Flunoxaprofeno, Flunoxaprofenum, (2s)-2-[2-(4-fluorophenyl)-1,3-benzoxazol-5-yl]propanoic acid, (S)-(+)-Flunoxaprofen, flunoxaprofene, (S)-2-(4-Fluorophenyl)-alpha-methyl-5-benzoxazoleacetic acid, (+)-2-(p-Fluorophenyl)-alpha-methyl-5-benzoxazoleacetic acid, (2S)-2-(2-(4-fluorophenyl)-1,3-benzoxazol-5-yl)propanoic acid, (+)-Flunoxaprofen