Products 76095-16-4
CAS 76095-16-4 appears in our catalog under these names: Enalapril Maleate, (S,S,S)-Enalapril Maleate, >95% (HPLC), Enalapril maleate 100 µg/mL in Acetonitrile, Enalapril Maleate, Enalapril Maleate/ 99.54% (existing batch purity). Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 100mg, 250mg, 5g, 10mg, 1ml, 1g, 100g.
Enalapril maleate is the maleic acid salt of enalapril. It contains one molecule of maleic acid for each molecule of enalapril. Following oral administration, the ethyl ester group of enalapril is hydrolysed to afford the corresponding carboxylic acid, enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor. Enalapril is thus a prodrug for enalaprilat (which, unlike enalapril, is not absorbed by mouth), and its maleate is used in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a prodrug. It contains an enalapril.
Source: ChEBI
| Molecular formula | C24H32N2O9 |
|---|---|
| Molecular weight | 492.5 g/mol |
| IUPAC name | (Z)-but-2-enedioic acid;(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
| InChIKey | OYFJQPXVCSSHAI-QFPUQLAESA-N |
| SMILES | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O.C(=C\C(=O)O)\C(=O)O |
Computed by PubChem (NCBI)