Products 83730-53-4
CAS 83730-53-4 appears in our catalog under these names: L-Buthionine-(S,R)-sulfoximine, >95% (HPLC), L-BUTHIONINE-(S,R)-SULFOXIMINE/ 98%, L–Buthionine–(S,R)–sulfoximine (L–Butionine sulfoximine), L-Buthionine-(S,R)-sulfoximine, L-Buthionine-(S,R)-sulfoximine, 99%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Thermo Scientific (Acros). Available pack sizes: 10g, 1g, 25mg, 50mg, 100mg, 10mM (in 1ml water), 0,25g, 0,5g.
L-buthionine-(S,R)-sulfoximine is a 2-amino-4-(S-butylsulfonimidoyl)butanoic acid which has S-configuration. It is a inhibitor of gamma-glutamylcysteine synthetase and glutathione (GSH) biosynthesis and is capable of enhancing the apoptotic effects of several chemotherapeutic agents. It has a role as a ferroptosis inducer and an EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor.
Source: ChEBI
| Molecular formula | C8H18N2O3S |
|---|---|
| Molecular weight | 222.31 g/mol |
| IUPAC name | (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid |
| InChIKey | KJQFBVYMGADDTQ-CVSPRKDYSA-N |
| SMILES | CCCCS(=N)(=O)CC[C@@H](C(=O)O)N |
Computed by PubChem (NCBI)
Synonyms:
L-Buthionine-(S,R)-sulfoximine, (2S)-2-Amino-4-(butylsulfonimidoyl)butanoic acid, (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic Acid, L-Buthionine (SR)-sulfoximine, D,L-Buthionine-S,R-sulfoximine, 1-beta-DL-Buthionine(S,R)sulfoximine, L-Buthionine-sulfoximine (H-L-Hcy(O,NH,Bu)-OH), (R*,S*)-(+-)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid, L-BSO, Butanoic acid, 2-amino-4-((R)-S-butylsulfonimidoyl)-, (2S)-rel-