Products 850649-61-5

CAS 850649-61-5 appears in our catalog under these names: Alogliptin (SYR–322), Alogliptin, Alogliptin, >95% (HPLC), Alogliptin/ 99.77% (existing batch purity), Alogliptin 98%. Offered by: GLPBio, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 5mg, on request, 100mg, 10mg, 250mg, 1mg, 2mg, 25mg.

Alogliptin (SYR–322)
GLPBio
  • size: 5mg, 10mg, 100mg, 10mM (in 1ml dmso)
  • Variants: 5
from 681.29
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Alogliptin
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 5g, 2g
  • Variants: 7
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Alogliptin, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 5mg
  • Variants: 3
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Alogliptin/ 99.77% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 392.86
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Alogliptin 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 8
from 120.06
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(R)-2-[6-[3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-ylmethyl]benzonitrile, 98%, 98%
Chemat
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 9
from 78.80
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Alogliptin, 99.93%
MedChemExpress
  • size: 5 mg, 100 mg, 50 mg, 10 mg
  • Variants: 5
from 384.71
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Alogliptin (Standard)
MedChemExpress
  • size: 50 mg, 10 mg, 25 mg, 5 mg
  • Variants: 5
from 784.09
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ALOGLIPTIN, 98%
Fluorochem
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 8
from 112.48
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Structural formula: {0} (CAS {1})

Alogliptin is a piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. It is a nitrile, a member of piperidines, a member of pyrimidines and a primary amino compound. It is a conjugate base of an alogliptin(1+).

Source: ChEBI

Identity
Molecular formulaC18H21N5O2
Molecular weight339.4 g/mol
IUPAC name2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile
InChIKeyZSBOMTDTBDDKMP-OAHLLOKOSA-N
SMILESCN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N

Computed by PubChem (NCBI)

Synonyms: Alogliptin, alogliptina, alogliptine, vipidia, alogliptinum, alogliptin tartrate, Alogliptin [INN], Trelagliptin Impurity 30, Alogliptin (Standard), ALOGLIPTIN [MI]
Related forms of this compound
2-[[6-[(3S)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
2-[[6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
2-[[6-[(3R)-3-aminopiperidin-1-yl]-2,4-dioxo-3-(trideuterio(113C)methyl)pyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
2-[[6-[(3R)-3-aminopiperidin-1-yl]-2,4-dioxo-3-(trideuteriomethyl)pyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
Isomers (same molecular formula)
2-[[3-methyl-2,4-dioxo-6-[[(3R)-piperidin-3-yl]amino]pyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
1-cyclopentyl-6-(1-ethylpyrazol-3-yl)-3-methylpyrazolo[5,4-b]pyridine-4-carboxylic acid C18H21N5O2
3-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile C18H21N5O2
2-[4-(2-pyrrolidin-1-ylethoxy)anilino]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one C18H21N5O2
6-N-[(2,5-dimethoxyphenyl)methyl]-6-N-methylquinazoline-2,4,6-triamine C18H21N5O2
2-[[4-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,6-dioxopyrimidin-1-yl]methyl]benzonitrile C18H21N5O2