Products 85441-61-8
CAS 85441-61-8 appears in our catalog under these names: Quinapril, 95%, Quinapril, 99%, Quinapril. Offered by: Combi-blocks, Chemat Brand, Hubei YoungXin, HPC Standards, MedChemExpress. Available pack sizes: 250mg, 1g, on request, 10mg, 25mg, 50mg, 100mg, 200mg.
Quinapril is a member of the class of isoquinolines that is (3S)-2-L-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid in which the alpha-amino group of the alanyl residue has been substituted by a 1-ethoxycarbonyl-4-phenylbutan-2-yl group (the all-S isomer). A prodrug for quinaprilat (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) used (generally as the hydrochloride salt) for the treatment of hypertension and congestive heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a prodrug. It is a tertiary carboxamide, an ethyl ester, a member of isoquinolines and a dicarboxylic acid monoester.
Source: ChEBI
| Molecular formula | C25H30N2O5 |
|---|---|
| Molecular weight | 438.5 g/mol |
| IUPAC name | (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid |
| InChIKey | JSDRRTOADPPCHY-HSQYWUDLSA-N |
| SMILES | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O |
Computed by PubChem (NCBI)