Products 85622-93-1
CAS 85622-93-1 appears in our catalog under these names: Temozolomide, Temozolomide - Bio-X â„¢, Temozolomide, >98.0%(HPLC), Temozolomide, 98.00%, 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 98%, 98%. Offered by: Chemat Brand, GLPBio, Biosynth, TCI, Thermo Scientific (Acros). Available pack sizes: on request, 10mg, 100mg, 1g, 200mg, 2g, 10mM (in 1ml dmso), 50mg.
Temozolomide is an imidazotetrazine that is 3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine which is substituted at positions 3, 4, and 8 by methyl, oxo, and carboxamide groups, respectively. A prodrug for MTIC (5-(3-methyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide, formed by spontaneous hydrolysis of temozolomide in the body), it is used as an oral alkylating agent for the treatment of newly diagnosed malignant glioblastoma multiforme (concomitantly with radiotherapy) and malignant melanoma. It has a role as an alkylating agent, an antineoplastic agent and a prodrug. It is a monocarboxylic acid amide, an imidazotetrazine and a triazene derivative.
Source: ChEBI
| Molecular formula | C6H6N6O2 |
|---|---|
| Molecular weight | 194.15 g/mol |
| IUPAC name | 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide |
| InChIKey | BPEGJWRSRHCHSN-UHFFFAOYSA-N |
| SMILES | CN1C(=O)N2C=NC(=C2N=N1)C(=O)N |
Computed by PubChem (NCBI)