Products 869298-31-7
CAS 869298-31-7 appears in our catalog under these names: FINO2/ 97.27% (existing batch purity), (–)–FINO2, (5α,8α)-8-(1,1-Dimethylethyl)-3-methyl-1,2-dioxaspiro[4.5]decane-3-ethanol, FINO2, 98.0%. Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 5 mg, 10 mg.
FINO2 is an oxaspiro compound that is 1,2-dioxaspiro[4.5]decane substituted by methyl, 2-hydroxyethyl and tert-butyl groups at positions 3, 3 and 8, respectivey (the 5s,8s-stereoisomer). It induces ferroptosis in cancer cells by indirectly inhibiting glutathione peroxidase 4 (GPX4) enzymatic function and directly oxidizes iron leading to widespread lipid peroxidation. It has a role as a ferroptosis inducer and an antineoplastic agent. It is a primary alcohol, an organic peroxide, an organic heterobicyclic compound and an oxaspiro compound.
Source: ChEBI
| Molecular formula | C15H28O3 |
|---|---|
| Molecular weight | 256.38 g/mol |
| IUPAC name | 2-(8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)ethanol |
| InChIKey | RWJLCLCUNHUSPG-UHFFFAOYSA-N |
| SMILES | CC1(CC2(CCC(CC2)C(C)(C)C)OO1)CCO |
Computed by PubChem (NCBI)
Synonyms:
2-(8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)ethanol, (5|A,8|A)-8-(1,1-dimethylethyl)-3-methyl-1,2-dioxaspiro[4.5]decane-3-ethanol, orb1689828, 2-{8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl}ethan-1-ol, 2-[(5s,8s)-8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl]ethan-1-ol, 2-(8-(tert-butyl)-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)ethan-1-ol, 2-[(5s,8s)-8-tert-butyl-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl]ethanol, 2-((5s,8s)-8-(tert-Butyl)-3-methyl-1,2-dioxaspiro[4.5]decan-3-yl)ethan-1-ol