Products 87333-19-5

CAS 87333-19-5 appears in our catalog under these names: Ramipril, Ramipril (1.0 mg/mL in Methanol), Ramipril, >95% (HPLC), Ramipril/ 98.51% (existing batch purity), Ramipril, 98% . Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 5x1ml, 250mg, 10mg, 100mg, 1g, 50mg, 500mg.

Structural formula: {0} (CAS {1})

Ramipril is a dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a prodrug, a matrix metalloproteinase inhibitor, a cardioprotective agent and a bradykinin receptor B2 agonist. It is an ethyl ester, a dicarboxylic acid monoester, an azabicycloalkane, a cyclopentapyrrole and a dipeptide. It is a conjugate acid of a ramipril(1-).

Source: ChEBI

Identity
Molecular formulaC23H32N2O5
Molecular weight416.5 g/mol
IUPAC name(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
InChIKeyHDACQVRGBOVJII-JBDAPHQKSA-N
SMILESCCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2[C@H]3CCC[C@H]3C[C@H]2C(=O)O

Computed by PubChem (NCBI)