Products 879085-55-9

CAS 879085-55-9 appears in our catalog under these names: Vismodegib, Vismodegib, >95% (HPLC), Vismodegib/ 99.99%, GDC–0449 (Vismodegib), Vismodegib 98%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 5mg, 50mg, 100mg, 200mg, 10mM (in 1ml dmso), 500mg.

Vismodegib
Chemat Brand, Biosynth, Sigma-Aldrich
  • size: on request, 1g, 0,5g, 5g
  • Variants: 7
from 2990.00
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Vismodegib, >95% (HPLC)
TRC
  • size: 10mg, 5mg
  • Variants: 2
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Vismodegib/ 99.99%
TargetMol
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 5
from 439.25
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GDC–0449 (Vismodegib)
GLPBio
  • size: 10mg, 200mg, 10mM (in 1ml dmso), 50mg
  • Variants: 5
from 578.32
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Vismodegib 98%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 120.06
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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide, 98%
Chemat
  • size: 10mg
  • Variants: 1
from 122.00
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2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide, 98%, 98%
Chemat
  • size: 10g, 100mg, 250mg, 1g
  • Variants: 5
from 242.00
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Vismodegib, 99.97%
MedChemExpress
  • size: 200 mg, 5 mg, 25 mg, 10 mg
  • Variants: 7
from 254.68
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Vismodegib (Standard)
MedChemExpress
  • size: 100 mg, 50 mg, 5 mg, 10 mg
  • Variants: 5
from 542.60
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Structural formula: {0} (CAS {1})

Vismodegib is a benzamide obtained by formal condensation between the carboxy group of 2-chloro-4-(methylsulfonyl)benzoic acid and the anilino group of 4-chloro-3-(pyridin-2-yl)aniline. Used for the treatment metastatic basal cell carcinoma. It has a role as a Hedgehog signaling pathway inhibitor, an antineoplastic agent, a teratogenic agent and a SMO receptor antagonist. It is a member of benzamides, a member of pyridines, a sulfone and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC19H14Cl2N2O3S
Molecular weight421.3 g/mol
IUPAC name2-chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide
InChIKeyBPQMGSKTAYIVFO-UHFFFAOYSA-N
SMILESCS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl

Computed by PubChem (NCBI)

Synonyms: Vismodegib, 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, Erivedge, HhAntag691, vismodegibum, 2-chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide, 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-(methylsulfonyl)benzamide, Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)-, R3616 cpd, Hedgehog Antagonist GDC-0449
Related forms of this compound
2-chloro-N-[4-chloro-2,3,6-trideuterio-5-(3,4,5,6-tetradeuterio-2-pyridinyl)phenyl]-4-methylsulfonylbenzamide C19H14Cl2N2O3S
2-chloro-N-[4-chloro-3-(3,4,5,6-tetradeuterio-2-pyridinyl)phenyl]-4-methylsulfonylbenzamide C19H14Cl2N2O3S