Products 906673-24-3
CAS 906673-24-3 appears in our catalog under these names: Crisaborole, Crisaborole, >95% (HPLC), AN–2728, Crisaborole, 98%, Crisaborole 98%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 100mg, 250mg, 25mg, 10mg, 50mg, 200mg, 5mg.
Crisaborole is a member of the class of benzoxaboroles that is 5-hydroxy-1,3-dihydro-2,1-benzoxaborole in which the phenolic hydrogen has been replaced by a 4-cyanophenyl group. A phosphodiesterase 4 inhibitor that is used for treatment of mild to moderate atopic dermatitis in children and adults. It has a role as a non-steroidal anti-inflammatory drug, an antipsoriatic and a phosphodiesterase IV inhibitor. It is a nitrile, an aromatic ether and a benzoxaborole.
Source: ChEBI
| Molecular formula | C14H10BNO3 |
|---|---|
| Molecular weight | 251.05 g/mol |
| IUPAC name | 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile |
| InChIKey | USZAGAREISWJDP-UHFFFAOYSA-N |
| SMILES | B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O |
Computed by PubChem (NCBI)
Synonyms:
Crisaborole, Eucrisa, Staquis, crisaborol, Crisaborole topical ointment 2%, 4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile, 4-((1-Hydroxy-1,3-dihydrobenzo(c)(1,2)oxaborol-6-yl)oxy)benzonitrile, Benzonitrile, 4-((1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy)-, crisaborolum