rac-Lasofoxifene

cas: 180915-78-0 — see every product listed under this CAS number, including other names

rac-Lasofoxifene (CAS 180915-78-0) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 1mg, 5mg. Offered by: TRC.

brandTRC
catalog numberTRC-L176490-10MG
cas180915-78-0
size10mg
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Available pack sizes

brand size price
TRC 10mg price on request
TRC 1mg price on request
TRC 5mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Lasofoxifene is a member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women. It has a role as an antineoplastic agent, a bone density conservation agent, an estrogen receptor antagonist, an estrogen receptor agonist and a cardioprotective agent. It is a member of naphthols, an aromatic ether, a member of tetralins and a N-alkylpyrrolidine.

Source: ChEBI

Identity
Molecular formulaC28H31NO2
Molecular weight413.5 g/mol
IUPAC name(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
InChIKeyGXESHMAMLJKROZ-IAPPQJPRSA-N
SMILESC1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: Lasofoxifene, Oporia, lasofoxifeno, lasofoxifenum, rac-Lasofoxifene, Lasofoxifene [INN], Lasofoxifene [INN:BAN], LASOFOXIFENE [MI], LASOFOXIFENE [MART.], LASOFOXIFENE [WHO-DD]
Related forms of this compound
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2
(5R,6S)-6-phenyl-5-[4-(1,1,2,2-tetradeuterio-2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol C28H31NO2