1-[7,8-Dihydro-2-[[9-(trans-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1,6-naphthyridin-6(5H)-yl]-2-hydroxyethanone, ≥98%
cas: 1401033-86-0 — see every product listed under this CAS number, including other names
1-[7,8-Dihydro-2-[[9-(trans-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1,6-naphthyridin-6(5H)-yl]-2-hydroxyethanone, ≥98% (CAS 1401033-86-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch112C28-1mg |
| cas | 1401033-86-0 |
| size | 1mg |
| availability | 0.2g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 218.00 Pln | |
| Chemat | 5mg | 611.60 Pln | |
| Chemat | 10mg | 818.00 Pln | |
| Chemat | 25mg | 1480.40 Pln | |
| Chemat | 50mg | 2267.60 Pln | |
| Chemat | 100mg | 3530.00 Pln |
properties
| purity | ≥98% |
|---|---|
| delivery time | 3 weeks |
AMG-925 is an organic heterotricyclic compound that is 9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidine which is substituted by a [6-(hydroxyacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]nitrilo group at position 2 and by a trans-4-methylcyclohexyl group at position 9. It is a FLT3 and CDK4 dual kinase inhibitor that has antineoplastic activity. Currently under clinical investigation in patients with relapsed or refractory acute myeloid leukemia (AML). It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a primary alpha-hydroxy ketone, an organic heterotricyclic compound, a secondary amino compound, a tertiary amino compound and a naphthyridine derivative.
Source: ChEBI
| Molecular formula | C26H29N7O2 |
|---|---|
| Molecular weight | 471.6 g/mol |
| IUPAC name | 2-hydroxy-1-[2-[[8-(4-methylcyclohexyl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-yl]amino]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone |
| InChIKey | BBUVDDPUURMFOX-UHFFFAOYSA-N |
| SMILES | CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5 |
Computed by PubChem (NCBI)
Synonyms:
orb1300495, s7533