AMG 925

cas: 1401033-86-0 — see every product listed under this CAS number, including other names

AMG 925 (CAS 1401033-86-0) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1g, 25mg, 5mg, 500mg, 50mg, 10mg. Offered by: GLPBio, Biosynth.

brandGLPBio
catalog numberGC14974-100
cas1401033-86-0
size100mg
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Available pack sizes

brand size price
GLPBio 100mg 2342.87 Pln
GLPBio 1g 9574.24 Pln
GLPBio 25mg 1374.00 Pln
GLPBio 5mg 779.58 Pln
GLPBio 500mg 5717.51 Pln
Biosynth 50mg price on request
Biosynth 10mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

AMG-925 is an organic heterotricyclic compound that is 9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidine which is substituted by a [6-(hydroxyacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]nitrilo group at position 2 and by a trans-4-methylcyclohexyl group at position 9. It is a FLT3 and CDK4 dual kinase inhibitor that has antineoplastic activity. Currently under clinical investigation in patients with relapsed or refractory acute myeloid leukemia (AML). It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a primary alpha-hydroxy ketone, an organic heterotricyclic compound, a secondary amino compound, a tertiary amino compound and a naphthyridine derivative.

Source: ChEBI

Identity
Molecular formulaC26H29N7O2
Molecular weight471.6 g/mol
IUPAC name2-hydroxy-1-[2-[[8-(4-methylcyclohexyl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-yl]amino]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone
InChIKeyBBUVDDPUURMFOX-UHFFFAOYSA-N
SMILESCC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5

Computed by PubChem (NCBI)

Synonyms: orb1300495, s7533

Also listed as

Amg 925, 95% Combi-blocks CAS 1401033-86-0
AMG 925, 99+% AmBeed CAS 1401033-86-0
AMG 925/ 99.42% (existing batch purity) TargetMol CAS 1401033-86-0
AMG 925 Biosynth CAS 1401033-86-0
1-[7,8-Dihydro-2-[[9-(trans-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1,6-naphthyridin-6(5H)-yl]-2-hydroxyethanone, ≥98%, ≥98% Chemat CAS 1401033-86-0
AMG 925, 99.02% MedChemExpress CAS 1401033-86-0