2-Methoxy-N-[(2e)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide, 99%, 99%
cas: 383432-38-0 — see every product listed under this CAS number, including other names
2-Methoxy-N-[(2e)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide, 99%, 99% (CAS 383432-38-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch118A2I-1mg |
| cas | 383432-38-0 |
| size | 1mg |
| availability | 0.015g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 146.00 Pln | |
| Chemat | 5mg | 170.00 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 3 weeks |
CP-724714 is a 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. It has a role as an antineoplastic agent, a hepatotoxic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer.
Source: ChEBI
| Molecular formula | C27H27N5O3 |
|---|---|
| Molecular weight | 469.5 g/mol |
| IUPAC name | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-6-yl]prop-2-enyl]acetamide |
| InChIKey | LLVZBTWPGQVVLW-SNAWJCMRSA-N |
| SMILES | CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)/C=C/CNC(=O)COC)C |
Computed by PubChem (NCBI)