Products 143621-35-6
CAS 143621-35-6 appears in our catalog under these names: 3-AP/ 97.33% (existing batch purity), 3–AP, 2-[(3-Aminopyridin-2-yl)methylene]hydrazinecarbothioamide, >98.0%(HPLC), Triapine 98%, Triapine, 99.78%. Offered by: TargetMol, GLPBio, TCI, Ambeed, MedChemExpress. Available pack sizes: 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 1mg.
Triapine is a thiosemicarbazone resulting from the formal condensation of the formyl group of 3-aminopicolinaldehyde with the non-thioacylated amino group of hydrazinecarbothioamide. It is a ribonucleotide reductase inhibitor that exhibits anti-cancer properties. It has a role as a radiosensitizing agent, an antineoplastic agent, an iron chelator, a neuroprotective agent, an apoptosis inducer and an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor. It is a thiosemicarbazone and an aminopyridine. It is functionally related to a 3-aminopicolinaldehyde.
Source: ChEBI
| Molecular formula | C7H9N5S |
|---|---|
| Molecular weight | 195.25 g/mol |
| IUPAC name | [(E)-(3-amino-2-pyridinyl)methylideneamino]thiourea |
| InChIKey | XMYKNCNAZKMVQN-NYYWCZLTSA-N |
| SMILES | C1=CC(=C(N=C1)/C=N/NC(=S)N)N |
Computed by PubChem (NCBI)
Synonyms:
Triapine, 3-Apct, 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone, Hydrazinecarbothioamide, 2-((3-amino-2-pyridinyl)methylene)-, Hydrazinecarbothioamide, 2-[(3-amino-2-pyridinyl)methylene]-, ((E)-((3-aminopyridin-2-yl)methylidene)amino)thiourea, [(E)-[(3-aminopyridin-2-yl)methylidene]amino]thiourea, Pan 811, [(3-aminopyridin-2-yl)methylideneamino]thiourea, (E)-2-((3-aminopyridin-2-yl)methylene)hydrazinecarbothioamide