4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide, 98%
cas: 755037-03-7 — see every product listed under this CAS number, including other names
4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide, 98% (CAS 755037-03-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 250mg, 500mg, 1g, 5g, 10g, 25g. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F361865-10MG |
| cas | 755037-03-7 |
| size | 10mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 10mg | 133.30 Pln | |
| Fluorochem | 100mg | 143.72 Pln | |
| Fluorochem | 250mg | 200.99 Pln | |
| Fluorochem | 500mg | 258.26 Pln | |
| Fluorochem | 1g | 320.74 Pln | |
| Fluorochem | 5g | 789.32 Pln | |
| Fluorochem | 10g | 1257.91 Pln | |
| Fluorochem | 25g | 2418.96 Pln |
properties
| purity | 98% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C21H15ClF4N4O3 |
|---|---|
| Molecular weight | 482.8 g/mol |
| IUPAC name | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide |
| InChIKey | FNHKPVJBJVTLMP-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F |
Computed by PubChem (NCBI)