Regorafenib
cas: 755037-03-7 — see every product listed under this CAS number, including other names
Regorafenib (CAS 755037-03-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 100mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: Chemat Brand, GLPBio, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | ULR078001 |
| cas | 755037-03-7 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Chemat Brand | on request | price on request | |
| GLPBio | 10mg | 573.64 Pln | |
| GLPBio | 100mg | 1046.37 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 625.12 Pln | |
| GLPBio | 50mg | 817.02 Pln | |
| Biosynth | 100mg | price on request | |
| Biosynth | 50mg | price on request | |
| Biosynth | 500mg | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C21H15ClF4N4O3 |
|---|---|
| Molecular weight | 482.8 g/mol |
| IUPAC name | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide |
| InChIKey | FNHKPVJBJVTLMP-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F |
Computed by PubChem (NCBI)