Products 755037-03-7

CAS 755037-03-7 appears in our catalog under these names: Regorafenib, 98%, Regorafenib, Regorafenib, >95% (HPLC), Regorafenib/ 99.87% (existing batch purity), Regorafenib, >98.0%(HPLC). Offered by: Combi-blocks, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 1g, 5g, 250mg, 100mg, on request, 10mg, 25mg, 5mg.

Regorafenib, 98%
Combi-blocks
  • size: 1g, 5g, 250mg, 100mg
  • Variants: 4
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Regorafenib
Chemat Brand, GLPBio, Biosynth
  • size: on request, 10mg, 100mg, 10mM (in 1ml dmso)
  • Variants: 9
from 573.64
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Regorafenib, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 25mg
  • Variants: 3
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Regorafenib/ 99.87% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 386.15
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Regorafenib, >98.0%(HPLC)
TCI
  • size: 25mg, 100mg
  • Variants: 2
from 354.37
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Regorafenib, 97%
Thermo Scientific (Acros)
  • size: 1g, 100MG
  • Variants: 2
from 984.43
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Regorafenib, 98.00%
Chemat
  • size: 100mg, 250mg, 25mg
  • Variants: 3
from 380.46
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Regorafenib 98%
Ambeed
  • size: 1mg, 250mg, 1g, 5g
  • Variants: 5
from 125.62
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4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 100mg
  • Variants: 10
from 78.80
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Regorafenib, 99.93%
MedChemExpress
  • size: 100 mg, 10 mg, 50 mg, 5 mg
  • Variants: 7
from 301.12
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Regorafenib (Standard)
MedChemExpress
  • size: 50 mg, 10 mg, 5 mg, 25 mg
  • Variants: 5
from 575.11
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4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide, 98%
Fluorochem
  • size: 10mg, 100mg, 250mg, 500mg
  • Variants: 8
from 133.30
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Regorafenib Monohydrate
Hubei YoungXin
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 5
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Structural formula: {0} (CAS {1})

Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC21H15ClF4N4O3
Molecular weight482.8 g/mol
IUPAC name4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
InChIKeyFNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILESCNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F

Computed by PubChem (NCBI)

Synonyms: Regorafenib, Stivarga, Regorafenibum, REGORAFENIB ANHYDROUS, Bay-734506, Regorafenib (BAY 73-4506), C21H15ClF4N4O3, Regorafenib,BAY 73-4506, Stivarga (TN), Regorafenib [INN]
Related forms of this compound
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide C21H15ClF4N4O3