Regorafenib, 97%

cas: 755037-03-7 — see every product listed under this CAS number, including other names

Regorafenib, 97% (CAS 755037-03-7) is a chemical reagent available from Chemat. Available pack sizes: 1g, 100MG. Offered by: Thermo Scientific (Acros).

brandThermo Scientific (Acros)
catalog number472550010
cas755037-03-7
size1g
availability availability
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Available pack sizes

brand size price
Thermo Scientific (Acros) 1g 2739.49 Pln
Thermo Scientific (Acros) 100MG 984.43 Pln

properties

delivery time2-3 weeks
categoryChemicals
purity97%
Structural formula: {0} (CAS {1})

Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC21H15ClF4N4O3
Molecular weight482.8 g/mol
IUPAC name4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
InChIKeyFNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILESCNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F

Computed by PubChem (NCBI)

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