ARP 101

cas: 849773-63-3 — see every product listed under this CAS number, including other names

ARP 101 (CAS 849773-63-3) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 25mg, 50mg, 100mg. Offered by: TargetMol, GLPBio, Biosynth.

brandTargetMol
catalog numberT22034-5mg
cas849773-63-3
size5mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
TargetMol 5mg 3952.01 Pln
GLPBio 5mg 1767.16 Pln
Biosynth 25mg price on request
Biosynth 50mg price on request
Biosynth 100mg price on request

properties

purityNo data
delivery timeon request
Structural formula: {0} (CAS {1})

N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide is a hydroxamic acid that is N-hydroxy-D-valinamide in which the alpha-amino group has been substituted by isopropoxy and [biphenyl]-4-ylsulfonyl groups. A selective matrix metalloproteinase-2 (MMP-2) inhibitor, it is one of the most potent inducers of autophagy. Its physiological roles include angiogenesis, cancer metastasis, embryogenesis, tissue remodeling in development, and wound healing. It has a role as an autophagy inducer, an antineoplastic agent, a melanin synthesis inhibitor and an EC 3.4.24.24 (gelatinase A) inhibitor. It is a hydroxamic acid and a D-valine derivative.

Source: ChEBI

Identity
Molecular formulaC20H26N2O5S
Molecular weight406.5 g/mol
IUPAC name(2R)-N-hydroxy-3-methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanamide
InChIKeyDGZZVIWCMGVHGV-LJQANCHMSA-N
SMILESCC(C)[C@H](C(=O)NO)N(OC(C)C)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2

Computed by PubChem (NCBI)

Synonyms: orb1704900, N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide, (R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-3-methyl-butyramide, N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-(propan-2-yloxy)-D-valinamide, N~2~-([1,1'-Biphenyl]-4-sulfonyl)-N-hydroxy-N~2~-[(propan-2-yl)oxy]-D-valinamide
Related forms of this compound
(2R)-N-hydroxy-3-methyl-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butanamide C20H26N2O5S
Isomers (same molecular formula)
(2S)-2-[[(2S)-1-[(2S)-3-acetylsulfanyl-2-methylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid C20H26N2O5S
2-[[4-[bis(prop-2-enyl)sulfamoyl]phenyl]carbamoyl]cyclohexane-1-carboxylic acid C20H26N2O5S
propan-2-yl 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoate C20H26N2O5S
2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide C20H26N2O5S
[(5S)-5-amino-5-carboxypentyl]azanium;2-[4-(thiophene-2-carbonyl)phenyl]propanoate C20H26N2O5S

Also listed as

ARP 101 GLPBio CAS 849773-63-3
ARP101, 99.39% MedChemExpress CAS 849773-63-3
(R)-N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-sulfonamido)-3-methylbutanamide, ≥96% Chemat CAS 849773-63-3