AS1842856 (Standard)

cas: 836620-48-5 — see every product listed under this CAS number, including other names

AS1842856 (Standard) (CAS 836620-48-5) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 25 mg, 5 mg, 50 mg, 100 mg. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-100596R-10 mg
cas	836620-48-5
size	10 mg
availability	Get quote

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Available pack sizes

brand	size	price
MedChemExpress	10 mg	1197.41 Pln
MedChemExpress	25 mg	2061.19 Pln
MedChemExpress	5 mg	839.82 Pln
MedChemExpress	50 mg	3036.43 Pln
MedChemExpress	100 mg	4494.65 Pln

properties

delivery time	over 3 weeks
purity	no data

AS1842856 is a quinolone that is 4-quinolone substituted at positions 1, 3, 5, 6 and 7 by ethyl, carboxy, amino, fluorine, and cyclohexylamino groups, respectively. It can directly bind to and block the transcription activity of the active forkhead box protein O1 (Foxo1), but not the Ser256-phosphorylated form. It induces cell death and growth arrest in Burkitt lymphoma cell lines at low concentrations. It has a role as a forkhead box protein O1 inhibitor, a hypoglycemic agent, an antineoplastic agent, an apoptosis inducer, an anti-obesity agent and an autophagy inhibitor. It is a quinolone, a quinolinemonocarboxylic acid, an organofluorine compound, a primary amino compound, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formula	C₁₈H₂₂FN₃O₃
Molecular weight	347.4 g/mol
IUPAC name	5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
InChIKey	MOMCHYGXXYBDCD-UHFFFAOYSA-N
SMILES	CCN1C=C(C(=O)C2=C1C=C(C(=C2N)F)NC3CCCCC3)C(=O)O