AZD–3463
cas: 1356962-20-3 — see every product listed under this CAS number, including other names
AZD–3463 (CAS 1356962-20-3) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14189-10 |
| cas | 1356962-20-3 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 774.90 Pln | |
| GLPBio | 100mg | 1664.19 Pln | |
| GLPBio | 5mg | 648.53 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 671.93 Pln | |
| GLPBio | 50mg | 1252.31 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
AZD3463 is a member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. It has a role as an autophagy inducer, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a member of indoles, a monomethoxybenzene, an organochlorine compound, an aminopyrimidine, an aminopiperidine, a secondary amino compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C24H25ClN6O |
|---|---|
| Molecular weight | 448.9 g/mol |
| IUPAC name | N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine |
| InChIKey | GCYIGMXOIWJGBU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
Computed by PubChem (NCBI)