AZD3463

cas: 1356962-20-3 — see every product listed under this CAS number, including other names

AZD3463 (CAS 1356962-20-3) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 50mg. Offered by: TRC, Biosynth.

brandTRC
catalog numberTRC-A808105-100MG
cas1356962-20-3
size100mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
TRC 100mg price on request
Biosynth 100mg price on request
Biosynth 50mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

AZD3463 is a member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. It has a role as an autophagy inducer, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a member of indoles, a monomethoxybenzene, an organochlorine compound, an aminopyrimidine, an aminopiperidine, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC24H25ClN6O
Molecular weight448.9 g/mol
IUPAC nameN-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
InChIKeyGCYIGMXOIWJGBU-UHFFFAOYSA-N
SMILESCOC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl

Computed by PubChem (NCBI)

Synonyms: ALK/IGF1R inhibitor, C24H25ClN6O, GCYIGMXOIWJGBU-UHFFFAOYSA-N, orb1226459, orb1306938, s7106

Also listed as

AZD–3463 GLPBio CAS 1356962-20-3
AZD-3463/ 99.13% (existing batch purity) TargetMol CAS 1356962-20-3
AZD-3463 99% Ambeed CAS 1356962-20-3
N-(4-(4-Aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine, 99%, 99% Chemat CAS 1356962-20-3
AZD-3463, 99.31% MedChemExpress CAS 1356962-20-3