AZD-3463, 99.31%
cas: 1356962-20-3 — see every product listed under this CAS number, including other names
AZD-3463, 99.31% (CAS 1356962-20-3) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 10 mg, 50 mg, 100 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-15609-10mM/1mL |
| cas | 1356962-20-3 |
| size | 10mM/1mL |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 440.44 Pln | |
| MedChemExpress | 10 mg | 570.47 Pln | |
| MedChemExpress | 50 mg | 1438.90 Pln | |
| MedChemExpress | 100 mg | 2493.08 Pln | |
| MedChemExpress | 5 mg | 412.57 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.31% |
AZD3463 is a member of the class of indoles that is 1H-indole substituted by a 2-[4-(4-aminopiperidin-1-yl)-2-methoxyanilino]-5-chloropyrimidin-4-yl group at position 3. It is an orally bioavailable dual inhibitor of ALK and IGF1R with Ki value of 0.75 nM for ALK. It has a role as an autophagy inducer, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a member of indoles, a monomethoxybenzene, an organochlorine compound, an aminopyrimidine, an aminopiperidine, a secondary amino compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C24H25ClN6O |
|---|---|
| Molecular weight | 448.9 g/mol |
| IUPAC name | N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine |
| InChIKey | GCYIGMXOIWJGBU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
Computed by PubChem (NCBI)