BMS–214662
cas: 195987-41-8 — see every product listed under this CAS number, including other names
BMS–214662 (CAS 195987-41-8) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 100mg, 10mM (in 1ml dmso), 25mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC32865-1 |
| cas | 195987-41-8 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 1060.41 Pln | |
| GLPBio | 10mg | 2998.14 Pln | |
| GLPBio | 100mg | 15045.74 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 2033.95 Pln | |
| GLPBio | 25mg | 5577.09 Pln | |
| GLPBio | 5mg | 1916.94 Pln | |
| GLPBio | 50mg | 8801.96 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
BMS-214662 is a member of the class of benzodiazepines that is 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine substituted by (1H-imidazol-5-yl)methyl, benzyl, (thiophen-2-yl)sulfonyl, and cyano groups at positions 1, 3R, 4 and 7, respectively. It is a potent inhibitor of farnesyltransferase (IC50 = 1.35nM) which was under clinical development for the treatment of solid tumors. It has a role as an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor and an apoptosis inducer. It is a nitrile, a member of benzenes, a benzodiazepine, a member of imidazoles, a member of thiophenes and a sulfonamide.
Source: ChEBI
| Molecular formula | C25H23N5O2S2 |
|---|---|
| Molecular weight | 489.6 g/mol |
| IUPAC name | (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile |
| InChIKey | OLCWFLWEHWLBTO-HSZRJFAPSA-N |
| SMILES | C1[C@H](N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5 |
Computed by PubChem (NCBI)