BMS-214662, 99.86%
cas: 195987-41-8 — see every product listed under this CAS number, including other names
BMS-214662, 99.86% (CAS 195987-41-8) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 25 mg, 5 mg, 10mM/1mL, 10 mg, 100 mg, 1 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-16111-50 mg |
| cas | 195987-41-8 |
| size | 50 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 10192.84 Pln | |
| MedChemExpress | 25 mg | 6500.86 Pln | |
| MedChemExpress | 5 mg | 2335.19 Pln | |
| MedChemExpress | 10mM/1mL | 2502.37 Pln | |
| MedChemExpress | 10 mg | 3575.14 Pln | |
| MedChemExpress | 100 mg | 16192.88 Pln | |
| MedChemExpress | 1 mg | 1072.02 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.86% |
BMS-214662 is a member of the class of benzodiazepines that is 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine substituted by (1H-imidazol-5-yl)methyl, benzyl, (thiophen-2-yl)sulfonyl, and cyano groups at positions 1, 3R, 4 and 7, respectively. It is a potent inhibitor of farnesyltransferase (IC50 = 1.35nM) which was under clinical development for the treatment of solid tumors. It has a role as an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor and an apoptosis inducer. It is a nitrile, a member of benzenes, a benzodiazepine, a member of imidazoles, a member of thiophenes and a sulfonamide.
Source: ChEBI
| Molecular formula | C25H23N5O2S2 |
|---|---|
| Molecular weight | 489.6 g/mol |
| IUPAC name | (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile |
| InChIKey | OLCWFLWEHWLBTO-HSZRJFAPSA-N |
| SMILES | C1[C@H](N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5 |
Computed by PubChem (NCBI)