Brequinar (Standard)
cas: 96187-53-0 — see every product listed under this CAS number, including other names
Brequinar (Standard) (CAS 96187-53-0) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 10 mg, 100 mg, 5 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-108325R-25 mg |
| cas | 96187-53-0 |
| size | 25 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 2711.35 Pln | |
| MedChemExpress | 10 mg | 1559.64 Pln | |
| MedChemExpress | 100 mg | 5948.22 Pln | |
| MedChemExpress | 5 mg | 1081.31 Pln | |
| MedChemExpress | 50 mg | 4007.03 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Brequinar is a quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties. It has a role as an anticoronaviral agent, an antiviral agent, an antimetabolite, an antineoplastic agent, an immunosuppressive agent, a pyrimidine synthesis inhibitor and an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor. It is a member of biphenyls, a monocarboxylic acid, a quinolinemonocarboxylic acid and a member of monofluorobenzenes. It is a conjugate acid of a brequinar(1-).
Source: ChEBI
| Molecular formula | C23H15F2NO2 |
|---|---|
| Molecular weight | 375.4 g/mol |
| IUPAC name | 6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid |
| InChIKey | PHEZJEYUWHETKO-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=CC(=C2)F)N=C1C3=CC=C(C=C3)C4=CC=CC=C4F)C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
Brequinar, brequinarum, 6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid, 4-Quinolinecarboxylic acid, 6-fluoro-2-(2'-fluoro(1,1'-biphenyl)-4-yl)-3-methyl-, 4-Quinolinecarboxylic acid, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-, 6-fluoro-2-(4-(2-fluorophenyl)phenyl)-3-methylquinoline-4-carboxylic acid, 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid, 6-Fluoro-2-(2'-fluoro(1,1'-biphenyl)-4-yl)-3-methyl-4-quinolinecarboxylic Acid, Bipenquinate, 6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid