Products 267243-28-7

CAS 267243-28-7 appears in our catalog under these names: Canertinib/ 99.18% (existing batch purity), Canertinib (CI–1033), Canertinib , Canertinib, >98.0%(HPLC)(qNMR), Canertinib 99%. Offered by: TargetMol, GLPBio, Chemat, TCI, Ambeed. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso), 1mg, 250mg.

Canertinib/ 99.18% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 4
from 392.86
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Canertinib (CI–1033)
GLPBio
  • size: 10mg, 100mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 583.00
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Canertinib
Chemat
  • size: 10mg, 1mg, 5mg
  • Variants: 3
from 646.83
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Canertinib, >98.0%(HPLC)(qNMR)
TCI
  • size: 25mg
  • Variants: 1
from 905.11
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Canertinib 99%
Ambeed
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 5
from 298.06
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Canertinib, 98%, 98%
Chemat
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 5
from 189.20
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Canertinib, 99.74%
MedChemExpress
  • size: 100 mg, 50 mg, 10 mg, 10mM/1mL
  • Variants: 6
from 296.47
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Canertinib (Standard)
MedChemExpress
  • size: 25 mg, 5 mg, 100 mg, 50 mg
  • Variants: 5
from 505.45
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Canertinib, 99%
Fluorochem
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 5
from 299.91
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Structural formula: {0} (CAS {1})

Canertinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is an organofluorine compound, a member of quinazolines, a member of morpholines and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC24H25ClFN5O3
Molecular weight485.9 g/mol
IUPAC nameN-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
InChIKeyOMZCMEYTWSXEPZ-UHFFFAOYSA-N
SMILESC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

Computed by PubChem (NCBI)

Synonyms: Canertinib, canertinibum, Canertinib (CI-1033), Canertinib [INN], Canertinib free base, Canertinib [INN:BAN], Canertinib - CI-1033, 267243-28-7 (free base), CANETINIB, CANERTINIB [MI]
Isomers (same molecular formula)
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide C24H25ClFN5O3
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide C24H25ClFN5O3
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide C24H25ClFN5O3
(Z)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide C24H25ClFN5O3
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide C24H25ClFN5O3
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide C24H25ClFN5O3