Crizotinib, 99.97%
cas: 877399-52-5 — see every product listed under this CAS number, including other names
Crizotinib, 99.97% (CAS 877399-52-5) is a chemical reagent available from Chemat. Available pack sizes: 500 mg, 5 mg, 100 mg, 10mM/1mL, 50 mg, 200 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-50878-500 mg |
| cas | 877399-52-5 |
| size | 500 mg |
| availability | In stock |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 500 mg | 1123.10 Pln | |
| MedChemExpress | 5 mg | 287.18 Pln | |
| MedChemExpress | 100 mg | 649.42 Pln | |
| MedChemExpress | 10mM/1mL | 412.57 Pln | |
| MedChemExpress | 50 mg | 491.52 Pln | |
| MedChemExpress | 200 mg | 751.58 Pln | |
| MedChemExpress | 10 mg | 384.71 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.97% |
Crizotinib is a 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). It has a role as an antineoplastic agent, a biomarker and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an enantiomer of an ent-crizotinib.
Source: ChEBI
| Molecular formula | C21H22Cl2FN5O |
|---|---|
| Molecular weight | 450.3 g/mol |
| IUPAC name | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine |
| InChIKey | KTEIFNKAUNYNJU-GFCCVEGCSA-N |
| SMILES | C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N |
Computed by PubChem (NCBI)