Crizotinib
cas: 877399-52-5 — see every product listed under this CAS number, including other names
Crizotinib (CAS 877399-52-5) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 0,25g, 0,1g, 1g, 0,5g, 2g. Offered by: Chemat Brand, Mikromol, Biosynth, Thermo Scientific (Acros).
| brand | Chemat Brand |
|---|---|
| catalog number | ULC123001 |
| cas | 877399-52-5 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Mikromol | 250mg | price on request | |
| Biosynth | 0,25g | price on request | |
| Biosynth | 0,1g | price on request | |
| Thermo Scientific (Acros) | 1g | 2222.77 Pln | |
| Thermo Scientific (Acros) | 250MG | 668.17 Pln | |
| Biosynth | 0,5g | price on request | |
| Biosynth | 1g | price on request | |
| Biosynth | 2g | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Crizotinib is a 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). It has a role as an antineoplastic agent, a biomarker and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an enantiomer of an ent-crizotinib.
Source: ChEBI
| Molecular formula | C21H22Cl2FN5O |
|---|---|
| Molecular weight | 450.3 g/mol |
| IUPAC name | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine |
| InChIKey | KTEIFNKAUNYNJU-GFCCVEGCSA-N |
| SMILES | C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N |
Computed by PubChem (NCBI)