Crizotinib, min. 95 %, 100 mg

cas: 877399-52-5 — see every product listed under this CAS number, including other names

Crizotinib, min. 95 %, 100 mg (CAS 877399-52-5) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: Roth.

brandRoth
catalog numberROTH-2K6Y.2
cas877399-52-5
size100mg
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Available pack sizes

brand size price
Roth 100mg 1127.99 Pln

properties

delivery time2 week
Structural formula: {0} (CAS {1})

Crizotinib is a 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). It has a role as an antineoplastic agent, a biomarker and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an enantiomer of an ent-crizotinib.

Source: ChEBI

Identity
Molecular formulaC21H22Cl2FN5O
Molecular weight450.3 g/mol
IUPAC name3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
InChIKeyKTEIFNKAUNYNJU-GFCCVEGCSA-N
SMILESC[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N

Computed by PubChem (NCBI)

Synonyms: Crizotinib, (R)-crizotinib, Xalkori, crizotinibum, MET Tyrosine Kinase Inhibitor PF-02341066, Crizotinib (PF-02341066), CRIZOTINIB [MART.], Crizotinib (PF-2341066), C21H22Cl2FN5O, VGH
Related forms of this compound
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(3,3,4,5,5-pentadeuteriopiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine C21H22Cl2FN5O
3-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine C21H22Cl2FN5O
Isomers (same molecular formula)
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine C21H22Cl2FN5O
5-ethyl-2-fluoro-4-[3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-6-yl]phenol;dihydrochloride C21H22Cl2FN5O

Also listed as

Crizotinib Chemat Brand CAS 877399-52-5
(R)–Crizotinib GLPBio CAS 877399-52-5
Crizotinib/ 99.35% (existing batch purity) TargetMol CAS 877399-52-5
Crizotinib - Bio-X â„¢ Biosynth CAS 877399-52-5
Crizotinib, 98.00% Chemat CAS 877399-52-5
Crizotinib, min. 95 %, 250 mg Roth CAS 877399-52-5
Crizotinib, min. 95 %, 500 mg Roth CAS 877399-52-5
Crizotinib, min. 95 %, 1 g Roth CAS 877399-52-5
Crizotinib, min. 95 %, BioScience Grade, 10 mg Roth CAS 877399-52-5
Crizotinib, 99.97% MedChemExpress CAS 877399-52-5
Crizotinib (Standard) MedChemExpress CAS 877399-52-5
Crizotinib, 95% Fluorochem CAS 877399-52-5

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