Deguelin, 99.20%

cas: 522-17-8 — see every product listed under this CAS number, including other names

Deguelin, 99.20% (CAS 522-17-8) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 5 mg, 50 mg, 10mM/1mL. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-13425-10 mg
cas	522-17-8
size	10 mg
availability	In stock

Available pack sizes

brand	size	price
MedChemExpress	10 mg	598.33 Pln
MedChemExpress	5 mg	380.06 Pln
MedChemExpress	50 mg	1801.13 Pln
MedChemExpress	10mM/1mL	403.28 Pln

properties

delivery time	1-2 weeks
purity	99.20%

Deguelin is a rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers. It has a role as an antiviral agent, an antineoplastic agent, a mitochondrial NADH:ubiquinone reductase inhibitor, an angiogenesis inhibitor, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is an aromatic ether, an organic heteropentacyclic compound, a diether and a member of rotenones.

Source: ChEBI

Identity
Molecular formula	C₂₃H₂₂O₆
Molecular weight	394.4 g/mol
IUPAC name	(1S,14S)-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one
InChIKey	ORDAZKGHSNRHTD-UXHICEINSA-N
SMILES	CC1(C=CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC)C

Computed by PubChem (NCBI)

Synonyms: Deguelin, (-)-cis-deguelin, (-)-Deguelin, DEGUELIN(-), KBioSS_001524, KBio2_001524, KBio3_002083, Tocris-1770, (-)-Deguelin;(-)-cis-Deguelin, Dequelin